Upton lies in an area well served by road and rail services, and is fortunate to have a local bus service.
First Great Western publish their timetables in PDF format.
The bus service No. 94, running between Didcot, West Hagbourne, Upton, Blewbury, East Hagbourne and Didcot, is operated by Thames Travel.
An excellent leaflet published by Sustrans details the cycle path between Didcot and Wantage and The Ridgeway, passing through Upton.